About the Practice
Problem Statement:

Wearable drug delivery device based on microneedles for efficient management of chemotherapy-induced nausea and vomiting (CINV) & nausea and vomiting in pregnancy (NVP)


A transepidermal anti-emetic drug-delivery patch using out-of-plane hollow silicon microneedle array is developed. Microneedles are pointed micron-scale structures that pierce the epidermal layer to reach dermal blood vessels and can directly release the drug in their vicinity. They are painless by virtue of avoiding significant contact with dermal sensory nerve endings. Microneedles’ mechanical stability, physicochemical properties, and performance in vitro, ex vivo, and in vivo studies are assessed The functional efficacy of the device in transepidermal delivery of anti-emetics, its programmability, ease of use, and biosafety are also established. It is successfully tested with model drugs and applied using thumb pressure. Hence, it is very easy to use with no or minimal supervision/training. The integrated hollow silicon microneedle-based transepidermal drug-delivery patch/system is able to handle the drug with different dosage efficaciously

About the Innovator

Knowledge Provider / Innovator: Bhushan N Kharbikar
Address: Main Gate Rd, IIT Area, Powai, Mumbai, Maharashtra 400076
City: Mumbai
State: Maharashtra
PIN Code 400076

Email: kharbikar.bhushan.n@iitb.ac.in
Contact No: 9860126770.0

Practice Details

Link: it enables us to manage the acute, anticipatory, delayed, breakthrough, refractory and chronic phases of CINV efficiently
Photo Links:

Problem Scale: India

GIAN Reference: GIAN/UAL/1067

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