Diagnosis of disease http://gyti.techpedia.in/files/GYTI-BOOK-color.pdf
Rapid Diagnostic Test (RDT) kits are not commonly available for many diseases prevalent in developing countries like ours. Even for such kits, the test procedures can be labour and time intensive, requiring expert supervision all the time. The present ‘paper-and-pencil’ diagnostic device is low-cost miniaturized (due to the innovative fabrication methodologies) and efficient (high throughput rate and multiplexable) device, which does not require an elaborate infrastructure and trained on-field pathologists through the implementation of colorimetric quantitative detection techniques (unlike the majority of the available RDT kits which are qualitative in nature). The proposed ‘point-of-care’ diagnostic device can be used for quantitative detection of a wide variety of biological analytes. Studies for detection of glucose (for diabetes) and bilirubin (for jaundice) have been undertaken. A stethoscope-shaped (‘Y’-shaped) ‘paper-and-pencil’ device is used. The pad at the end of one of the arms of the ‘Y’-section is spotted with a specific reagent for glucose detection (diabetes), while the pad at the end of the other arm is spotted with the pertinent reagent for bilirubin detection (jaundice). The sample (blood serum) is placed on the pad at the end of the leg of the ‘Y’ channel. The applied electric field augments the liquid flow through the paper channel to the respective test pads, where it reacts with the reagents; thereby turning the paper pad into different colors). The level of glucose or bilirubin can be quantitatively estimated by matching the respectively obtained colors with the pertinent color keys/calibration charts. The electrically-mediated flow through the paper channel significantly improves the repeatability, controllability and response time of the low-cost device. The researchers have also standardized an even more economic and simpler methodology for fabricating such ‘paper-and-pencil’ devices by using normal inkjet printing.
Link: Ultra-low cost Stethoscope-shaped (‘Y’-shaped) ‘paper-and-pencil’ device The level of glucose or bilirubin can be quantitatively estimated by matching the respectively obtained colors with the pertinent color keys/calibration charts. The electrically-mediated flow through the paper channel significantly improves the repeatability, controllability and response time of the low-cost device http://gyti.techpedia.in/files/GYTI-BOOK-color.pdf
Manufacturing Capacity: a) Turnkey solution, b) Design Support, c) Sub-contracting, d) Licensing, e) Franchising, f) Any other:
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